Zestril medicine
Zestril tablets contain the active ingredient lisinopril, which is a type of medicine called ACE inhibitor. (NB. Lisinopril tablets can also be without stamps, that is, as general medicine.)
ACE inhibitors work by blocking the effect of compounds in the body called angiotensin-converting enzyme (ACE). Usually ACE produces another set called angiotensin II, as a natural part of the body controls blood pressure. Angiotensin II causes blood vessels to constrict and narrow, which increases the pressure inside blood vessels.
It blocks the effects of lisinopril ACE, it reduces the production of angiotensin II. This means that the blood vessels can relax and widen. The overall effect of this is to reduce blood pressure, so lisinopril can be used to reduce high blood pressure.
Reduced pressure in blood vessels means that the heart does not have to work as hard to pump blood around the body. This means that the ACE inhibitors, such as lisinopril can also be used to improve the symptoms of heart failure, when the heart is not pumping as efficiently as it should be, and to improve survival after a heart attack.
Tuesday, February 12, 2008
Zestril tablets
The patient information leaflet
Zestril tablets
lisinopril
2.5 mg, 5 mg, 10 mg and 20 mg
Read all of this leaflet carefully before you start taking this medicine.
Keep this leaflet. You may have to read it again.
If you have any further questions, please ask your doctor or pharmacist.
This medication was prescribed for you personally, and you should not pass it to others. It may harm them, even if their symptoms are the same as yours.
This booklet
1. With Zestril is that it is used to
2. Before I take Zestril
3. How to take Zestril
4. Possible side effects
5. Storage Zestril
6. Additional information
Go to the top
The active substance in Zestril tablets is lisinopril (as dihydrate).
Other ingredients mannitol, hydrogen, calcium phosphate, corn starch, pregelatinised starches and magnesium stearate. In addition, the pink tablets contain red iron oxide (E172).
Zestril tablets come in 4 strengths containing either 2.5 mg, 5 mg, 10 mg or 20 mg of lisinopril (as dihydrate).
Zestril tablets
At 2.5 mg tablets white and 5 mg, 10 mg and 20 mg tablets pink. They come in boxes containing a calendar blister packs of 28 tablets.
In Marketing Authorisations for Zestril tablets held
AstraZeneca UK Limited
600 Green Possibility
Luton
LU1 3LU
UK
Zestril tablets manufactured by
AstraZeneca UK Limited
Silk Road Business Park
Macclesfield
Cheshire
SK10 2NA
UK
Zestril tablets
lisinopril
2.5 mg, 5 mg, 10 mg and 20 mg
Read all of this leaflet carefully before you start taking this medicine.
Keep this leaflet. You may have to read it again.
If you have any further questions, please ask your doctor or pharmacist.
This medication was prescribed for you personally, and you should not pass it to others. It may harm them, even if their symptoms are the same as yours.
This booklet
1. With Zestril is that it is used to
2. Before I take Zestril
3. How to take Zestril
4. Possible side effects
5. Storage Zestril
6. Additional information
Go to the top
The active substance in Zestril tablets is lisinopril (as dihydrate).
Other ingredients mannitol, hydrogen, calcium phosphate, corn starch, pregelatinised starches and magnesium stearate. In addition, the pink tablets contain red iron oxide (E172).
Zestril tablets come in 4 strengths containing either 2.5 mg, 5 mg, 10 mg or 20 mg of lisinopril (as dihydrate).
Zestril tablets
At 2.5 mg tablets white and 5 mg, 10 mg and 20 mg tablets pink. They come in boxes containing a calendar blister packs of 28 tablets.
In Marketing Authorisations for Zestril tablets held
AstraZeneca UK Limited
600 Green Possibility
Luton
LU1 3LU
UK
Zestril tablets manufactured by
AstraZeneca UK Limited
Silk Road Business Park
Macclesfield
Cheshire
SK10 2NA
UK
Zestril package insert
Zestril package insert
I'm a 56 yr. old female and have been taking blood pressure meds. for about 12 yrs. I'm currently taking triamterene and atenolol. I've been getting headaches off and on for the past month where I mostly feel very light headed. I also get Charlie horses in my calves at night and I have had chronic muscle pain in my calves for almost a year. I saw my doctor last week and my blood pressure was elevated (160/100) and so she added zestril to my meds. My blood pressure was only taken once during the office visit. Enough? When I checked my BP at home this morning it was 137/81 I'm wondering if either the triamterene or the atenolol can be giving me the headaches and/or the muscle aches. I skipped the triamterene yesterday and only took the atenolol and zestril and I felt great. This morning I took all three and so far, I still feel pretty good, except for the muscle pain in my calves. I will be going back to the drs. office this week to have my BP checked.
Doctor's Answer Zestril package insert
Dear cmb,
Triamterene can cause low potassium and calcium which may cause muscle cramps. Although headaches are described in the package insert for triamterene as a possible side-effect it is not commonly reported. In would be unlikely that atenolol or zestril would cause these side-effects but cannot be excluded for sure without a trial of stopping them. I would ask your doctor about stopping the triamterene. In addition be sure to show him the log of your home blood pressures. This will assist him in adjusting your medicatons.
by terre, Nov 08, 2001 12:00AM
I was on triamterene for over a year and had constant leg cramps at night or the feeling of leg muscles "crawling". I am on zestril alone now and have lost the leg cramps so I'm assuming it was from triamterene. I've have a sense of smell disorder which I just realized started around the same time I started taking Zestril. Everything tastes and smells like some kind of chemical. Anyone have this with zestril?
Zestril package insert
I'm a 56 yr. old female and have been taking blood pressure meds. for about 12 yrs. I'm currently taking triamterene and atenolol. I've been getting headaches off and on for the past month where I mostly feel very light headed. I also get Charlie horses in my calves at night and I have had chronic muscle pain in my calves for almost a year. I saw my doctor last week and my blood pressure was elevated (160/100) and so she added zestril to my meds. My blood pressure was only taken once during the office visit. Enough? When I checked my BP at home this morning it was 137/81 I'm wondering if either the triamterene or the atenolol can be giving me the headaches and/or the muscle aches. I skipped the triamterene yesterday and only took the atenolol and zestril and I felt great. This morning I took all three and so far, I still feel pretty good, except for the muscle pain in my calves. I will be going back to the drs. office this week to have my BP checked.
Doctor's Answer Zestril package insert
Dear cmb,
Triamterene can cause low potassium and calcium which may cause muscle cramps. Although headaches are described in the package insert for triamterene as a possible side-effect it is not commonly reported. In would be unlikely that atenolol or zestril would cause these side-effects but cannot be excluded for sure without a trial of stopping them. I would ask your doctor about stopping the triamterene. In addition be sure to show him the log of your home blood pressures. This will assist him in adjusting your medicatons.
by terre, Nov 08, 2001 12:00AM
I was on triamterene for over a year and had constant leg cramps at night or the feeling of leg muscles "crawling". I am on zestril alone now and have lost the leg cramps so I'm assuming it was from triamterene. I've have a sense of smell disorder which I just realized started around the same time I started taking Zestril. Everything tastes and smells like some kind of chemical. Anyone have this with zestril?
Zestril package insert
Zestril blood pressure
Zestril (lisinopril)
Zestril blood pressure
How does it work?
Zestril tablets contain the active ingredient lisinopril, which is a type of medicine called ACE inhibitor. (NB. Lisinopril tablets can also be without stamps, that is, as general medicine.)
ACE inhibitors work by blocking the effect of compounds in the body called angiotensin-converting enzyme (ACE). Usually ACE produces another set called angiotensin II, as a natural part of the body controls blood pressure. Angiotensin II causes blood vessels to constrict and narrow, which increases the pressure inside blood vessels.
It blocks the effects of lisinopril ACE, it reduces the production of angiotensin II. This means that the blood vessels can relax and widen. The overall effect of this is to reduce blood pressure, so lisinopril can be used to reduce high blood pressure.
Reduced pressure in blood vessels means that the heart does not have to work as hard to pump blood around the body. This means that the ACE inhibitors, such as lisinopril can also be used to improve the symptoms of heart failure, when the heart is not pumping as efficiently as it should be, and to improve survival after a heart attack.
With this appointment?
High blood pressure is not known causes
High blood pressure as a result of compression or blockage of arteries that carry blood to the kidneys (renovascular hypertension)
Heart failure
Improved survival after heart attack
Diabetic kidney disease.
Attention!
Zestril blood pressure
Some people may experience dizziness caused by low blood pressure in the first few days after taking the medication and, in particular, in the first dose. For this reason, the first dose should preferably be taken at bedtime. Your doctor may want you to take the first dose of the drug under medical supervision in hospital, if you are over 70, have low blood pressure, low levels of fluid and salt in the blood (for example, due to dehydration), unstable or severe heart failure , kidney problems, or are taking high-dose diuretic medications, several diuretic drugs, or some other drugs that dilate your blood vessels.
If you feel dizzy during treatment that can be released to lay until the symptoms pass. If you are affected should avoid potentially hazardous perform tasks such as driving or operation of machinary. If you often feel dizzy, you let your doctor know how your dose of this medication, you may need to decline.
Alcohol can increase blood pressure to reduce the influence of the drug, which can increase dizziness, and may increase the risk of fainting.
ACE inhibitors can sometimes cause allergic reaction called angioedema. This is more likely to occur in black patients. Stop this medicine, and consult your doctor immediately if you experience difficulty breathing or swallowing, or swelling of the person lips, tongue, throat, arms, legs or ankles, taking this medicine.
Your blood pressure, kidney function and the amount of potassium in the blood should be regularly monitored, and you have this medicine.
Use with caution in
Zestril blood pressure
Older people
Reduced renal function
Narrowing of arteries that supply blood to the kidneys (renal artery stenosis)
People with a low level of liquid or salt levels in the body, for example, in connection with diuretic therapy, low-sodium diet, diarrhoea and vomiting
People taking other medications for high blood pressure, in particular, Diuretics (see at the end of newsletter)
People with the hardening of arteries, for example, in the center of (heart disease), brain (brain), or feet (peripheral vascular disease)
A low pressure (hypotension)
Severe heart failure
Diabetes
Diseases that affect connective tissue, such as scleroderma, systemic lupus erythematosus (collagen vascular disease)
People with renal insufficiency requiring hemodialysis certain type (high-flux membranes)
People receiving treatment for the removal of certain types of fats from the blood through your computer (LDL apheresis)
People are being treated to reduce allergies to bee or wasp stings (desensitisation).
It would not be used
History swelling lips, tongue or face (angioedema), the cause is not known, or as a result of prior use for ACE inhibitor medicine
Hereditary angioedema
The narrowing of the main artery of the body (aortic stenosis)
Heart disease is characterized by thickening of the heart muscle and internal blockage inside the hearts (hypertrophic obstructive cardiomyopathy)
Expansion chamber heart (right ventricle) because of high blood pressure in the pulmonary artery (cor pulmonale)
Pregnancy.
This medicine is not recommended for children.
This medicine should not be used if you are allergic to one or any of its components. Please let your doctor or pharmacist if you have already experienced such an allergy. If you think you have experienced an allergic reaction, stop using the drug, and inform your doctor or pharmacist immediately.
Pregnancy and breastfeeding
Zestril blood pressure
Some medicines should not be used during pregnancy or breast-feeding. However, other drugs can be safely used during pregnancy or breast-feeding mothers to provide benefits outweigh the risks to the unborn child. Always, let your doctor if you are pregnant or plan to become pregnant before using any medication.
This medicine should not be used during pregnancy, especially during the second and third trimesters, as it could be harmful to the unborn child. Get medical consultation with the doctor. If you become pregnant while taking this medicine, and the deadline to submit consult your doctor immediately. However, in some cases, where a drug is considered vital to the mother, treatment can be continued.
It is not known if the medicine is transferred into breast milk. It should be used with caution in nursing mothers, and only if the benefits to the mother outweigh any risks to the nursing infant. Discuss this with your doctor.
Side effects
Medicines and their possible side effects can affect individuals in different ways. Some of the side effects, which, as you know, associated with this medicine. Because a side effect described here, it does not mean that all people using the medication will experience as any side effect.
Dizziness
Headache
Unrest in the intestine, such as diarrhea, constipation, nausea, vomiting and abdominal pain
Fatigue
Dry cough
A low pressure (hypotension)
Sensing weakness (asthenia)
Rash
Dry mouth
Raising the level of potassium in the blood (hyperkalaemia)
Chest pain (angina)
Faster than normal heartbeat (tachycardia)
Changes in mood
The difficulty in sleeping (insomnia)
Pins and needles sensations (paraesthesia)
Shortage of breathing (shortness of breath)
Impotence
Alterations to taste
Severe swelling of the lips, face, tongue or larynx (angioedema - Preventing see above)
Diseases of the kidneys, liver or blood
Side effects listed above, may not include all of these side effects reported drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information with medicine or consult your doctor or pharmacist.
Zestril blood pressure
How does it work?
Zestril tablets contain the active ingredient lisinopril, which is a type of medicine called ACE inhibitor. (NB. Lisinopril tablets can also be without stamps, that is, as general medicine.)
ACE inhibitors work by blocking the effect of compounds in the body called angiotensin-converting enzyme (ACE). Usually ACE produces another set called angiotensin II, as a natural part of the body controls blood pressure. Angiotensin II causes blood vessels to constrict and narrow, which increases the pressure inside blood vessels.
It blocks the effects of lisinopril ACE, it reduces the production of angiotensin II. This means that the blood vessels can relax and widen. The overall effect of this is to reduce blood pressure, so lisinopril can be used to reduce high blood pressure.
Reduced pressure in blood vessels means that the heart does not have to work as hard to pump blood around the body. This means that the ACE inhibitors, such as lisinopril can also be used to improve the symptoms of heart failure, when the heart is not pumping as efficiently as it should be, and to improve survival after a heart attack.
With this appointment?
High blood pressure is not known causes
High blood pressure as a result of compression or blockage of arteries that carry blood to the kidneys (renovascular hypertension)
Heart failure
Improved survival after heart attack
Diabetic kidney disease.
Attention!
Zestril blood pressure
Some people may experience dizziness caused by low blood pressure in the first few days after taking the medication and, in particular, in the first dose. For this reason, the first dose should preferably be taken at bedtime. Your doctor may want you to take the first dose of the drug under medical supervision in hospital, if you are over 70, have low blood pressure, low levels of fluid and salt in the blood (for example, due to dehydration), unstable or severe heart failure , kidney problems, or are taking high-dose diuretic medications, several diuretic drugs, or some other drugs that dilate your blood vessels.
If you feel dizzy during treatment that can be released to lay until the symptoms pass. If you are affected should avoid potentially hazardous perform tasks such as driving or operation of machinary. If you often feel dizzy, you let your doctor know how your dose of this medication, you may need to decline.
Alcohol can increase blood pressure to reduce the influence of the drug, which can increase dizziness, and may increase the risk of fainting.
ACE inhibitors can sometimes cause allergic reaction called angioedema. This is more likely to occur in black patients. Stop this medicine, and consult your doctor immediately if you experience difficulty breathing or swallowing, or swelling of the person lips, tongue, throat, arms, legs or ankles, taking this medicine.
Your blood pressure, kidney function and the amount of potassium in the blood should be regularly monitored, and you have this medicine.
Use with caution in
Zestril blood pressure
Older people
Reduced renal function
Narrowing of arteries that supply blood to the kidneys (renal artery stenosis)
People with a low level of liquid or salt levels in the body, for example, in connection with diuretic therapy, low-sodium diet, diarrhoea and vomiting
People taking other medications for high blood pressure, in particular, Diuretics (see at the end of newsletter)
People with the hardening of arteries, for example, in the center of (heart disease), brain (brain), or feet (peripheral vascular disease)
A low pressure (hypotension)
Severe heart failure
Diabetes
Diseases that affect connective tissue, such as scleroderma, systemic lupus erythematosus (collagen vascular disease)
People with renal insufficiency requiring hemodialysis certain type (high-flux membranes)
People receiving treatment for the removal of certain types of fats from the blood through your computer (LDL apheresis)
People are being treated to reduce allergies to bee or wasp stings (desensitisation).
It would not be used
History swelling lips, tongue or face (angioedema), the cause is not known, or as a result of prior use for ACE inhibitor medicine
Hereditary angioedema
The narrowing of the main artery of the body (aortic stenosis)
Heart disease is characterized by thickening of the heart muscle and internal blockage inside the hearts (hypertrophic obstructive cardiomyopathy)
Expansion chamber heart (right ventricle) because of high blood pressure in the pulmonary artery (cor pulmonale)
Pregnancy.
This medicine is not recommended for children.
This medicine should not be used if you are allergic to one or any of its components. Please let your doctor or pharmacist if you have already experienced such an allergy. If you think you have experienced an allergic reaction, stop using the drug, and inform your doctor or pharmacist immediately.
Pregnancy and breastfeeding
Zestril blood pressure
Some medicines should not be used during pregnancy or breast-feeding. However, other drugs can be safely used during pregnancy or breast-feeding mothers to provide benefits outweigh the risks to the unborn child. Always, let your doctor if you are pregnant or plan to become pregnant before using any medication.
This medicine should not be used during pregnancy, especially during the second and third trimesters, as it could be harmful to the unborn child. Get medical consultation with the doctor. If you become pregnant while taking this medicine, and the deadline to submit consult your doctor immediately. However, in some cases, where a drug is considered vital to the mother, treatment can be continued.
It is not known if the medicine is transferred into breast milk. It should be used with caution in nursing mothers, and only if the benefits to the mother outweigh any risks to the nursing infant. Discuss this with your doctor.
Side effects
Medicines and their possible side effects can affect individuals in different ways. Some of the side effects, which, as you know, associated with this medicine. Because a side effect described here, it does not mean that all people using the medication will experience as any side effect.
Dizziness
Headache
Unrest in the intestine, such as diarrhea, constipation, nausea, vomiting and abdominal pain
Fatigue
Dry cough
A low pressure (hypotension)
Sensing weakness (asthenia)
Rash
Dry mouth
Raising the level of potassium in the blood (hyperkalaemia)
Chest pain (angina)
Faster than normal heartbeat (tachycardia)
Changes in mood
The difficulty in sleeping (insomnia)
Pins and needles sensations (paraesthesia)
Shortage of breathing (shortness of breath)
Impotence
Alterations to taste
Severe swelling of the lips, face, tongue or larynx (angioedema - Preventing see above)
Diseases of the kidneys, liver or blood
Side effects listed above, may not include all of these side effects reported drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information with medicine or consult your doctor or pharmacist.
Zestril Medication
GENERIC NAME: lisinopril
BRAND NAME: Zestril, Prinivil
Zestril Medication
CLASS DRUG AND MECHANISM: Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. Angiotensin is a chemical that is made in the body permanently. He narrows blood vessels and thereby maintains (elevates) blood pressure. When the enzyme is blocked by lisinopril, angiotensin can not be converted into its active form. As a result, blood vessels dilate and blood pressure falls.
PRESCRIPTION: Yes
Zestril Medication
GENERIC accessible: Yes
PREPARATION: 2.5, 5, 10, 20 and 40 mg oral tablets.
STORAGE: Lisinopril should be stored in a dry place at 15-30 ° C (59-86 ° F).
PRESCRIBED FOR: Lisinopril is used to treat high blood pressure, heart failure and improve survival after heart attack (myocardial infarction).
DOSING: Lisinopril be taken in doses, particularly under the guidance of a doctor. Lisinopril can be taken with or without food. Lisinopril should be taken at the same time each day to maintain a consistent blood levels of lisinopril. Lisinopril should not be taken within two hours after the antacid because antacid connects lisinopril and prevents its absorption. At doses of lisinopril often reduced gradually when to stop.
The starting dose of lisinopril 5 mg a day, and effective dose range for the treatment of heart failure is 5-40 mg per day. The dose may be increased to 10 mg every 2 weeks to achieve maximum effect. The maximum dose is 40 mg per day.
The starting dose of lisinopril for the treatment of high blood pressure is 10 mg per day. The normal dose range 20-40 mg per day. A dose of 80 mg is not much more effective than 40 mg.
The treatment of a heart attack (myocardial infarction) begins with 5 mg then 5 mg in 24 hours, 10 mg in 48 hours, then 10 mg per day. Treatment continued for 6 weeks.
DRUG INTERACTIONS: In general, lisinopril should not take potassium supplements with Diuretics, or that the preservation of potassium [such as hydrochlorothiazide / triamterene (Dyazide)], because the blood levels of potassium may rise to dangerous levels.
PREGNANCY: Lisinopril should not be taken during pregnancy because fetuses and newborns died when lisinopril administration during pregnancy.
NURSING MOTHERS: It is not known whether lisinopril excretion in breast milk.
SIDE EFFECTS: first lisinopril doses may cause dizziness due to the lower blood pressure. Lisinopril can cause nausea, headaches, anxiety, insomnia, drowsiness, nasal congestion and sexual dysfunction. Lisinopril must be stopped if there are symptoms or signs of allergic reactions, including swelling sense of the person, lips, tongue and throat. Severe allergic reactions (anaphylaxis), and sometimes rash. Rarely, lisinopril can cause a drop in red blood cells, white blood cells and platelets.
Lisinopril can reduce kidney function, and each person takes the medicine should have their kidney function checked.
Zestril Medication 2008
BRAND NAME: Zestril, Prinivil
Zestril Medication
CLASS DRUG AND MECHANISM: Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. Angiotensin is a chemical that is made in the body permanently. He narrows blood vessels and thereby maintains (elevates) blood pressure. When the enzyme is blocked by lisinopril, angiotensin can not be converted into its active form. As a result, blood vessels dilate and blood pressure falls.
PRESCRIPTION: Yes
Zestril Medication
GENERIC accessible: Yes
PREPARATION: 2.5, 5, 10, 20 and 40 mg oral tablets.
STORAGE: Lisinopril should be stored in a dry place at 15-30 ° C (59-86 ° F).
PRESCRIBED FOR: Lisinopril is used to treat high blood pressure, heart failure and improve survival after heart attack (myocardial infarction).
DOSING: Lisinopril be taken in doses, particularly under the guidance of a doctor. Lisinopril can be taken with or without food. Lisinopril should be taken at the same time each day to maintain a consistent blood levels of lisinopril. Lisinopril should not be taken within two hours after the antacid because antacid connects lisinopril and prevents its absorption. At doses of lisinopril often reduced gradually when to stop.
The starting dose of lisinopril 5 mg a day, and effective dose range for the treatment of heart failure is 5-40 mg per day. The dose may be increased to 10 mg every 2 weeks to achieve maximum effect. The maximum dose is 40 mg per day.
The starting dose of lisinopril for the treatment of high blood pressure is 10 mg per day. The normal dose range 20-40 mg per day. A dose of 80 mg is not much more effective than 40 mg.
The treatment of a heart attack (myocardial infarction) begins with 5 mg then 5 mg in 24 hours, 10 mg in 48 hours, then 10 mg per day. Treatment continued for 6 weeks.
DRUG INTERACTIONS: In general, lisinopril should not take potassium supplements with Diuretics, or that the preservation of potassium [such as hydrochlorothiazide / triamterene (Dyazide)], because the blood levels of potassium may rise to dangerous levels.
PREGNANCY: Lisinopril should not be taken during pregnancy because fetuses and newborns died when lisinopril administration during pregnancy.
NURSING MOTHERS: It is not known whether lisinopril excretion in breast milk.
SIDE EFFECTS: first lisinopril doses may cause dizziness due to the lower blood pressure. Lisinopril can cause nausea, headaches, anxiety, insomnia, drowsiness, nasal congestion and sexual dysfunction. Lisinopril must be stopped if there are symptoms or signs of allergic reactions, including swelling sense of the person, lips, tongue and throat. Severe allergic reactions (anaphylaxis), and sometimes rash. Rarely, lisinopril can cause a drop in red blood cells, white blood cells and platelets.
Lisinopril can reduce kidney function, and each person takes the medicine should have their kidney function checked.
Zestril Medication 2008
Zestril 10 mg
Zestril 10 mg
1. Name drug
Zestril 2.5 mg, 5 mg, 10 mg, 20 mg tablets.
Zestril 10 mg
2. Qualitative and quantitative composition
Each tablet contains lisinopril dihydrate equivalent to 2.5 mg, 5 mg, 10 mg or 20 mg of anhydrous lisinopril.
For fillers, see List of 6.1 fillers.
3. PHARMACEUTICALS FORM
2.5 mg tablets are white, round and biconvex. They have a diameter of 6 mm.
5 mg tablets, pink, round and biconvex. They have a diameter of 6 mm.
10 mg tablets, pink, round and biconvex. They have a diameter of 8 mm.
20 mg tablets, pink, round and biconvex. They have a diameter of 8 mm.
All pills are marked on one side with a number denoting tablet strength.
4. CLINICAL PARTICULARS
4.1 Therapeutic indications
Hypertension
Treatment of hypertension.
Zestril 10 mg
Heart failure
The treatment of the symptoms of heart failure.
Acute myocardial infarction
Short-term (6 weeks) treatment of haemodynamically stable patients within 24 hours after acute myocardial infarction.
Renal complications of diabetes
Treatment of kidney disease in hypertensive patients with Type 2 diabetes and incipient nephropathy (see section 5.1).
Posology 4.2 and the method of administration
Zestril must be made orally in a single daily dose. Like all other drugs taken once a day, should take Zestril about the same time every day. Depreciation Zestril tablets is not affected by food.
The dose should be individualised according to the patient's profile and blood pressure response (see section 4.4).
Hypertension
Zestril may be used as monotherapy or in combination with other classes of antihypertensive therapy.
Starting dose
In patients with hypertension usual recommended starting dose is 10 mg. Patients with highly activated renin-angiotensin-aldosterone system (in particular, renovascular hypertension, salt and / or layer volume, cardiac decompensation or severe hypertension) may experience excessive pressure in autumn after the initial dose. A 2.5-5 mg starting dose is recommended for such patients and the initiation of treatment should be conducted under medical supervision. A lower starting dose is required if renal view (see Table 1 below).
The maintenance dose
Usually the effective maintenance dosage of 20 mg administered in a single daily dose. In general, if the desired therapeutic effect can not be achieved in the period of 2 to 4 weeks, at a dose level, the dose could be further increased. The maximum dose used in the long-term, controlled clinical trials with 80 mg per day.
Diuretic patients
Symptomatic hypotension may occur after the beginning of therapy with Zestril. This is more likely in patients who are being treated currently Diuretics. Attention is therefore recommended, as these patients can be the volume and / or salt depleted. If possible, the diuretic should be dispensed from 2 to 3 days before the start of therapy with Zestril. In hypertensive patients in the diuretic which can not be terminated, with Zestril therapy should begin with 5 mg dose. Renal function and serum potassium should be monitored. In subsequent Zestril doses should be adjusted according to blood pressure response. If required, diuretic therapy may be renewed (see section 4.4 and 4.5).
Zestril 10 mg
Dosage adjustment in violation of kidney
The dosage in patients with renal damage should be based on creatinine clearance as indicated in Table 1.
Table 1 Dosage adjustment in violation of kidney
1. Name drug
Zestril 2.5 mg, 5 mg, 10 mg, 20 mg tablets.
Zestril 10 mg
2. Qualitative and quantitative composition
Each tablet contains lisinopril dihydrate equivalent to 2.5 mg, 5 mg, 10 mg or 20 mg of anhydrous lisinopril.
For fillers, see List of 6.1 fillers.
3. PHARMACEUTICALS FORM
2.5 mg tablets are white, round and biconvex. They have a diameter of 6 mm.
5 mg tablets, pink, round and biconvex. They have a diameter of 6 mm.
10 mg tablets, pink, round and biconvex. They have a diameter of 8 mm.
20 mg tablets, pink, round and biconvex. They have a diameter of 8 mm.
All pills are marked on one side with a number denoting tablet strength.
4. CLINICAL PARTICULARS
4.1 Therapeutic indications
Hypertension
Treatment of hypertension.
Zestril 10 mg
Heart failure
The treatment of the symptoms of heart failure.
Acute myocardial infarction
Short-term (6 weeks) treatment of haemodynamically stable patients within 24 hours after acute myocardial infarction.
Renal complications of diabetes
Treatment of kidney disease in hypertensive patients with Type 2 diabetes and incipient nephropathy (see section 5.1).
Posology 4.2 and the method of administration
Zestril must be made orally in a single daily dose. Like all other drugs taken once a day, should take Zestril about the same time every day. Depreciation Zestril tablets is not affected by food.
The dose should be individualised according to the patient's profile and blood pressure response (see section 4.4).
Hypertension
Zestril may be used as monotherapy or in combination with other classes of antihypertensive therapy.
Starting dose
In patients with hypertension usual recommended starting dose is 10 mg. Patients with highly activated renin-angiotensin-aldosterone system (in particular, renovascular hypertension, salt and / or layer volume, cardiac decompensation or severe hypertension) may experience excessive pressure in autumn after the initial dose. A 2.5-5 mg starting dose is recommended for such patients and the initiation of treatment should be conducted under medical supervision. A lower starting dose is required if renal view (see Table 1 below).
The maintenance dose
Usually the effective maintenance dosage of 20 mg administered in a single daily dose. In general, if the desired therapeutic effect can not be achieved in the period of 2 to 4 weeks, at a dose level, the dose could be further increased. The maximum dose used in the long-term, controlled clinical trials with 80 mg per day.
Diuretic patients
Symptomatic hypotension may occur after the beginning of therapy with Zestril. This is more likely in patients who are being treated currently Diuretics. Attention is therefore recommended, as these patients can be the volume and / or salt depleted. If possible, the diuretic should be dispensed from 2 to 3 days before the start of therapy with Zestril. In hypertensive patients in the diuretic which can not be terminated, with Zestril therapy should begin with 5 mg dose. Renal function and serum potassium should be monitored. In subsequent Zestril doses should be adjusted according to blood pressure response. If required, diuretic therapy may be renewed (see section 4.4 and 4.5).
Zestril 10 mg
Dosage adjustment in violation of kidney
The dosage in patients with renal damage should be based on creatinine clearance as indicated in Table 1.
Table 1 Dosage adjustment in violation of kidney
Zestril 20 mg
Zestril. Zestril 20 mg
Zestril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure. Zestril also can be used with other medicine for the treatment of congestive heart disease or improve survival in some patients after a heart attack. Zestril can be used to treat other conditions as determined by a physician.
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Zestril
• Zestril 2.5mg, pills
• Zestril 20 mg 5mg, pills
• Zestril 10mg, pills
• Zestril 20mg, pills
• Zestril 30mg, pills
• Zestril 40mg, pills
Zestril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure. Zestril also can be used with other medicine for the treatment of congestive heart disease or improve survival in some patients after a heart attack. Zestril can be used to treat other conditions as determined by a physician.
Click on drugs in the list below to see prices and information.
Zestril
• Zestril 2.5mg, pills
• Zestril 20 mg 5mg, pills
• Zestril 10mg, pills
• Zestril 20mg, pills
• Zestril 30mg, pills
• Zestril 40mg, pills
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